Impact of IDH1 R132 Mutations and an IDH1 Single Nucleotide Polymorphism in Cytogenetically Normal Acute Myeloid Leukemia: SNP rs11554137 Is an Adverse …

…, I Schäfer, O Ottmann, M Lübbert, W Heit… - Journal of clinical …, 2010 - ascopubs.org
Purpose We assessed the prognostic impact of IDH1 R132 mutations and a known single
nucleotide polymorphism (SNP) located in the same exon of the IDH1 gene in patients with …

Prognostic impact of IDH2 mutations in cytogenetically normal acute myeloid leukemia

…, D Hoelzer, M Lübbert, W Heit… - Blood, The Journal …, 2010 - ashpublications.org
Mutations in the nicotinamide adenine dinucleotide phosphate+–dependent isocitrate
dehydrogenase gene 2 (IDH2) have recently been found in patients with acute myeloid …

Bone marrow transplantation for chronic myeloid leukaemia in first chronic phase: importance of a graft‐versus‐leukaemia effect

…, S Tura, A Iacone, G Torlontano, W Heit… - British journal of …, 1988 - Wiley Online Library
We analysed the incidence of graft failure, graft‐versus‐host disease (GVHD) and relapse of
leukaemia in 208 patients undergoing allogeneic bone marrow transplantation (BMT) for …

Single Nucleotide Polymorphism in the Mutational Hotspot of WT1 Predicts a Favorable Outcome in Patients With Cytogenetically Normal Acute Myeloid Leukemia

…, K Döhner, O Ottmann, M Lübbert, W Heit… - Journal of Clinical …, 2010 - ascopubs.org
Purpose We assessed the prognostic impact of a known single nucleotide polymorphism
(SNP) located in the mutational hotspot of WT1 in patients with cytogenetically normal acute …

Prognostic value of minimal residual disease quantification by real-time reverse transcriptase polymerase chain reaction in patients with core binding factor leukemias

…, O Ottmann, M Lubbert, H Dohner, W Heit… - Journal of clinical …, 2003 - ascopubs.org
Purpose: In patients with acute myeloblastic leukemia with t (8; 21) or inv (16) aberrations
(core binding factor [CBF] leukemias), minimal residual disease (MRD) can be sensitively …

Patterns of growth in human septal cartilage: a review of new approaches

U Vetter, W Pirsig, G Helbing, W Heit… - International journal of …, 1984 - Elsevier
Recent results of the growth activities of the septal cartilage in children, adolescents, and
adults are reviewed. Cartilaginous biopsies were obtained during septoplasty. Matrix …

Development of advanced HTR fuel elements

H Nabielek, W Kühnlein, W Schenk, W Heit… - … Engineering and Design, 1990 - Elsevier
Spherical fuel elements with coated particles are the essential constituents of the integrity of
a pebble-bed reactor, particularly with respect to fission product retention. While all gas …

Characteristics of Hodgkin's disease-derived cell lines.

…, C Fonatsch, J Gerdes, M Schaadt, W Heit… - Cancer treatment …, 1982 - europepmc.org
In the last 3 years we were able to establish five long-term in vitro cell cultures from biopsy
specimens taken preterminally from four patients with histologically proven Hodgkin's …

[HTML][HTML] Pitfalls of vaccinations with WT1-, Proteinase3-and MUC1-derived peptides in combination with MontanideISA51 and CpG7909

…, S van Dorp, S Hol, PD Greenberg, W Heit… - Cancer immunology …, 2011 - Springer
T cells with specificity for antigens derived from Wilms Tumor gene (WT1), Proteinase3 (Pr3),
and mucin1 (MUC1) have been demonstrated to lyse acute myeloid leukemia (AML) blasts …

Human fetal and adult chondrocytes. Effect of insulinlike growth factors I and II, insulin, and growth hormone on clonal growth.

U Vetter, J Zapf, W Heit, G Helbing… - The Journal of …, 1986 - Am Soc Clin Investig
Clonal proliferation of freshly isolated human fetal chondrocytes and adult chondrocytes in
response to human insulinlike growth factors I and II (IGF I, IGF II), human biosynthetic …