Folliculin (FLCN)-interacting proteins 1 and 2 (FNIP1, FNIP2) are homologous binding
partners of FLCN, a tumor suppressor for kidney cancer. Recent studies have revealed …

Summary Background Birt-Hogg-Dubé (BHD) syndrome, caused by germline alteration of
folliculin (FLCN) gene, develops hybrid oncocytic/chromophobe tumour (HOCT) and …

Hereditary leiomyomatosis and renal cell cancer (HLRCC) is a rare autosomal dominant
disorder that results from a germline mutation in the fumarate hydratase gene (FH) …

Aims Hereditary leiomyomatosis and renal cell cancer (HLRCC) is an autosomal dominant
disorder caused by germline mutations in fumarate hydratase (FH). Affected families have …

Birt-Hogg-Dubé syndrome is an inherited disorder caused by germline mutations of the
folliculin gene (FLCN). The affected patients are prone to developing renal cell carcinomas …

B irt‐H ogg‐D ubé syndrome (BHD) is an autosomal dominant disorder associated with a
germline mutation of folliculin (FLCN). The affected families are at a high risk for developing …

Objectives: TRIM21 is an E3 ubiquitin ligase for interferon regulatory factors (IRFs) that are
involved in innate and acquired immunity. Here, we evaluated the role of TRIM21 in the …

Summary Birt-Hogg-Dubé syndrome (BHD) is a familial disorder associated with a germline
mutation of FLCN that is a tumor suppressor gene. Patients with BHD have high risks for …

Hereditary renal cell carcinomas (RCCs) are life-threatening disorders not only for the
patients but also for their relatives. Birt–Hogg–Dubé syndrome (BHD) is an autosomal …

A regulatory mechanism for SLC family transporters, critical transporters for sodium and
glucose reabsorptions in renal tubule, is incompletely understood. Here, we report an …