Statistics from Altmetric.com
A 21-year-old woman presented with an upper left lobe mass, discovered in a context of asthenia, dyspnoea, wheezing, flushes and evening fever. Initial CT imaging revealed a heterogeneous mass predominantly endobronchial into the bronchus of the lingula with latero-aortic and perihilar adenopathies. Positron emission tomography-CT scan found a hypermetabolism of the tumour (maximum standard uptake value (SUVmax=10) as well as in mediastinal lymph nodes (SUV=2.2). Initial fibroscopy performed found a stenosing endoluminal tumour. Left superior lobectomy and mediastinal lymph node dissection were performed.
Review the high quality, interactive digital Aperio slide at http://virtualacp.com/JCPCases/jclinpath-2018-205259/ and consider your diagnosis.
Q1: What is your diagnosis?
Hematoxylin eosin safron (HES) slide 1:
Pulmonary myxoid sarcoma
Inflammatory myofibroblastic tumour
Q2: What additional analyse(s) do you perform?
EWSR1 fluorescence in situ hybridisation …
Handling editor Iskander Chaudhry.
Contributors GB and AM-L wrote the article. M-CC and MD contributed to the diagnosis. All authors contributed to the proof-reading of the article.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; internally peer reviewed.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.