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Virtual case of the month
Unexpected pulmonary tumour in a young woman
  1. Geoffroy Boulle1,2,
  2. Margot Dupeux1,
  3. Marie-Christine Charpentier1,
  4. Fréderique Larousserie1,
  5. Jean François Régnard3,
  6. Diane Damotte1,2,
  7. Audrey Mansuet-Lupo1,2
  1. 1 Department of Pathology, HUPC, Cochin Hospital, Paris, France
  2. 2 INSERM UMR 1138, Team 'Cancer, Immune Control, and Escape' Cordeliers Research Center, Paris, France
  3. 3 Department of Thoracic Surgery, HUPC Cochin Hospital, Paris, France
  1. Correspondence to Dr Audrey Mansuet-Lupo, Department of pathology, HUPC, hôpital Cochin, Paris 75014, France; audreylupo{at}yahoo.fr

https://doi.org/10.1136/jclinpath-2018-205259

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    Clinical question

    A 21-year-old woman presented with an upper left lobe mass, discovered in a context of asthenia, dyspnoea, wheezing, flushes and evening fever. Initial CT imaging revealed a heterogeneous mass predominantly endobronchial into the bronchus of the lingula with latero-aortic and perihilar adenopathies. Positron emission tomography-CT scan found a hypermetabolism of the tumour (maximum standard uptake value (SUVmax=10) as well as in mediastinal lymph nodes (SUV=2.2). Initial fibroscopy performed found a stenosing endoluminal tumour. Left superior lobectomy and mediastinal lymph node dissection were performed.

    Review the high quality, interactive digital Aperio slide at http://virtualacp.com/JCPCases/jclinpath-2018-205259/ and consider your diagnosis.

    Q1: What is your diagnosis?

    Hematoxylin eosin safron (HES) slide 1:

    1. Carcinoïd tumour

    2. Pulmonary myxoid sarcoma

    3. Inflammatory myofibroblastic tumour

    4. Myxoid liposarcoma

    5. Pulmonary haematoma

    Q2: What additional analyse(s) do you perform?

    1. EWSR1 fluorescence in situ hybridisation …

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    Footnotes

    • Handling editor Iskander Chaudhry.

    • Contributors GB and AM-L wrote the article. M-CC and MD contributed to the diagnosis. All authors contributed to the proof-reading of the article.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; internally peer reviewed.