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Unexpected pulmonary tumour in a young woman
  1. Geoffroy Boulle1,2,
  2. Margot Dupeux1,
  3. Marie-Christine Charpentier1,
  4. Fréderique Larousserie1,
  5. Jean François Régnard3,
  6. Diane Damotte1,2,
  7. Audrey Mansuet-Lupo1,2
  1. 1 Department of Pathology, HUPC, Cochin Hospital, Paris, France
  2. 2 INSERM UMR 1138, Team 'Cancer, Immune Control, and Escape' Cordeliers Research Center, Paris, France
  3. 3 Department of Thoracic Surgery, HUPC Cochin Hospital, Paris, France
  1. Correspondence to Dr Audrey Mansuet-Lupo, Department of pathology, HUPC, hôpital Cochin, Paris 75014, France; audreylupo{at}

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Clinical question

A 21-year-old woman presented with an upper left lobe mass, discovered in a context of asthenia, dyspnoea, wheezing, flushes and evening fever. Initial CT imaging revealed a heterogeneous mass predominantly endobronchial into the bronchus of the lingula with latero-aortic and perihilar adenopathies. Positron emission tomography-CT scan found a hypermetabolism of the tumour (maximum standard uptake value (SUVmax=10) as well as in mediastinal lymph nodes (SUV=2.2). Initial fibroscopy performed found a stenosing endoluminal tumour. Left superior lobectomy and mediastinal lymph node dissection were performed.

Review the high quality, interactive digital Aperio slide at and consider your diagnosis.

Q1: What is your diagnosis?

Hematoxylin eosin safron (HES) slide 1:

  1. Carcinoïd tumour

  2. Pulmonary myxoid sarcoma

  3. Inflammatory myofibroblastic tumour

  4. Myxoid liposarcoma

  5. Pulmonary haematoma

Q2: What additional analyse(s) do you perform?

  1. EWSR1 fluorescence in situ hybridisation …

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  • Handling editor Iskander Chaudhry.

  • Contributors GB and AM-L wrote the article. M-CC and MD contributed to the diagnosis. All authors contributed to the proof-reading of the article.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.